2006 Refereed Papers
Amin, A.A., Faux, N.G., Fenalti, G., Williams, G., Bernadou, A., Daglish, K., Keefe, K., Middleton, S., Rae, J., Tetis, K., Law, R.H., Fulton, K.F., Rossjohn, J., Whisstock, J.C. and Buckle, A.M. (2006) Managing and mining protein crystallization data, Proteins, 62, 4-7.
Archbold, J.K., Macdonald, W.A., Miles, J.J., Brennan, R.M., Kjer-Nielsen, L., McCluskey, J., Burrows, S.R. and Rossjohn, J. (2006) Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is resultant of highly focused, peptide-dependent structural mimicry, Journal of Biological Chemistry, 281, 34324-34332.
Autelitano, D.J., Rajic, A., Smith, A.I., Berndt, M.C., Ilag, I.L. and Vadas, M. (2006) The Cryptome: a subset of the proteome comprised of cryptic peptides with distinct bioactivities, Drug Discovery Today, 11, 306-314.
Atkin, J.D., Farg, A., Turner, B.J., Tomas, D., Lysaght, J.A., Nunan, J., Rembach, A., Nagley, P., Beart, P.M., Cheema, S.S., and Horne, M.K. (2006) Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein disulfide isomerase with superoxide dismutase 1, Journal of Biological Chemistry, 281, 30152-30165.
Bannam, T.L., Teng, W.L., Bulach, D., Lyras, D. and & Rood, J.I. (2006) Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens, Journal of Bacteriology, 188, 4942-4951. Link to full text
Boyce, J.D. and Adler, B. (2006) How does Pasteurella multocida respond to the host environment? Current Opinion in Microbiology, 9, 117-122.
Boyce, J., Cullen, P., Nguyen, V., Wilkie, I. and Adler, B. (2006) Analysis of the Pasteurella multocida outer membrane sub-proteome and its response to the in vivo environment of the natural host, Proteomics, 6, 870-880.
Bulach, D.M., Zuerner, R.L., Wilson, P., Seemann, T., McGrath, A., Cullen, P.A., Davis, J., Johnson, M., Kuczek, E., Alt, D.P., Peterson-Burch, B., Coppel, R.L., Rood, J.I., Davies, J.K. and Adler, B. (2006) Genomic reduction in Leptospira borgpetersenii reflects limited transmission potential, Proceedings of the National Academy of Sciences of the United States of America, 103, 14560-14565. Link to full text
Bushell, S.R., Bottomley, S., Rossjohn, J. and Beddoe, T. (2006) Tracking the unfolding pathway of a multi-repeat protein via tryptophan scanning: Evidence of localised instability in the mitochondrial import receptor TOM70, Journal of Biological Chemistry, 281, 24345-24350.
Burrows, S.R., Rossjohn, J. and McCluskey, J. (2006) Have we cut ourselves too short in mapping CTL epitopes? Trends in Immunology, 27, 11-16.
Chow, M.K., Amin, A.A., Fulton, K.F., Whisstock, J.C., Buckle, A.M. Bottomley, S.P. (2006) The REFOLD database: a tool for the optimization of protein expression and refolding, Nucleic Acids Research, 34 (Database issue), D207-212.
Chow, M.K., Amin, A.A., Fulton, K.F., Whisstock, J.C., Buckle, A.M. and Bottomley, S.P. (2006) REFOLD: An analytical database of protein refolding methods, Protein Expression and Purification, 46, 166-171. Link to full text
Chuang, Y.H., Lian, Z.X., Tsuneyama, K., Chiang, B.L., Ansari, A.A., Coppel, R.L. and Gershwin, M.E. (2006) Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis, Journal of Autoimmunity, 26, 232-240.
Clarke, C., Kuruppu, S., Reeve, S., Smith, A.I. and Hodgson, W.C. (2006) Oxylepitoxin-1, a reversible neurotoxin from the venom of the inland taipan (Oxyuranus microlepidotus), Peptides, 27, 2655-2660.
Clements, C.S., Dunstone, M.A., MacDonald, W.A., McCluskey, J. and Rossjohn, J. (2006) Specificity on a knife-edge: the alphabeta T cell receptor, Current Opinion in Structural Biology, 16, 787-795.
Clements, C.S., Kjer-Nielsen, L., Kostenko, L., McCluskey, J. and Rossjohn, J. (2006) The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt, Acta crystallographica. Section F, Structural biology and crystallization communications, 62, 70-73. Link to full text
Cooke, B.M., Buckingham, D.W., Glenister, F.K., Fernandez, K.M., Bannister, L.H., Marti, M., Mohandas, N. and Coppel, R.L. (2006) A Maurer’s cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells, Journal of Cell Biology, 172, 899-908. Link to full text
Davies, J.K. and Rood, J.I. (Invited Review) (2006) Bacterial gene regulation: an overview, Microbiology Australia, 27, 99-100.
Davies, J.K. (Invited Review) (2006) Control of transcription by nucleoid proteins, Microbiology Australia, 27, 112-114.
Ely, L.K., Beddoe, T., Clements, C.S., Matthews, J.M., Purcell, A.W., Kjer-Nielsen, L., McCluskey, J. and Rossjohn, J., (2006) Disparate thermodynamics governing TcR - pMHC-I interactions implicate extrinsic factors in guiding MHC-restriction, Proceedings of the National Academy of Sciences of the United States of America, 103, 6641-6646. Link to full text
Fisher, D.J., Fernandez Miyakawa, M.E., Sayeed, S., Poon, R., Adams, V., Rood, J.I., Uzal, F.A. and McClane, B.A. (2006) Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model, Infection and Immunity, 74, 5200-5210.
Gunesekere, I.C., Kahler, C.M., Ryan, C.S., Snyder, L.A.S., Saunders, N.J., Rood, J.I. and Davies, J.K. (2006) Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase, Journal of Bacteriology, 188, 3463-3469. Link to full text
Gunesekere, I.C., Kahler, C.M., Powell, D.R., Snyder, L.A.S., Saunders, N.J., Rood, J.I. and Davies, J.K. (2006) Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae, Journal of Bacteriology, 188, 4769-4776. Link to full text
Hansen, T.M., Smith, D.J. and Nagley, P. (2006) Smac-DIABLO is not released from mitochondria during apoptotic signalling in cells deficient in cytochrome c, Cell Death and Differentiation, 13, 1181-1190.
Hampson, D.J., La, T., Adler, B. and Trott, D.J. (2006) Proposed revisions to the nomenclature for Brachyspira membrane proteins and lipoproteins, Microbiology, 152, 1-2.
Harper, M., Boyce, J.D. and Adler, B. (Invited Review) (2006) Pasteurella multocida pathogenesis: 125 years after Pasteur, FEMS Microbiology Letters, 265, 1-10.
He, X.S., Ansari, A.A., Ridgway, W.M., Coppel, R.L. and Gershwin, M.E. (2006) New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis, Cellular Immunology, 239, 1-13.
Hennebry, S.C., Law, R.H.P., Richardson, S.J., Buckle, A.M. and Whisstock, J.C. (2006) The crystal structure of the transthyretin-like protein from Salmonella Dublin, a prokaryote 5-hydroxyisourate hydrolase, Journal of Molecular Biology, 359, 1389-1399.
Hoare, H.L., Sullivan, L.C., Pietra, G., Clements, C.S., Lee, E.J., Ely, L.K., Beddoe, T., Falco, M., Kjer-Nielsen, L., Reid, H.H., McCluskey, J., Moretta, L., Rossjohn, J. and Brooks, A.G. (2006) Structural basis for a major histocompatibility complex class Ib-restricted T cell response, Nature Immunology, 7, 256-264.
Howden, B.P., Johnson, P.D., Ward, P.B., Stinear, T.P. and Davies, J.K. (2006) Isolates with low-level vancomycin resistance associated with persistent methicillin-resistant Staphylococcus aureus bacteraemia, Antimicrobial Agents and Chemotherapy, 50, 3039-3047. Link to full text
Huntington, N.D., Tomioka, R., Clavarino, C., Chow, C., Linares, A.M., Mana, D.P., Rossjohn, J., Cachero, T.G., Qian, F., Kalled, S.L., Bernard, C.C. and Reid, H.H. (2006) A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses, International Immunology, 18, 1473-1485.
Kaiserman, D., Bird, C.H., Sun, J., Matthews, A., Ung, K., Whisstock, J.C., Thompson, P.E., Trapani, J.A. and Bird, P.I. (2006) The major human and mouse granzymes are structurally and functionally divergent, Journal of Cell Biology, 175, 619-630.
Kaiserman, D., Whisstock, J.C. and Bird, P.I. (2006) Mechanisms of serpin dysfunction in disease, Expert Reviews in Molecular Medicine, 8, 1-19.
Kats, L.M., Black, C.G., Proellocks, N.I. and Coppel, R.L. (2006) Plasmodium rhoptries: how things went pear-shaped, Trends in Parasitology, 22, 269-276.
Keyburn, A.L., Sheedy, S.A., Ford, M.E., Williamson, M.M., Awad, M.M., Rood, J.I. and Moore, R.J. (2006) The alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens, Infection and Immunity, 74, 6496-6500. Link to full text
Kjer-Nielsen, L., Borg, N.A., Pellicci, D.G., Beddoe, T., Kostenko, L., Clements, C.S., Williamson, N.A., Smyth, M.J., Besra, G.S., Reid, H.H., Bharadwaj, M., Godfrey, D.I., Rossjohn, J. and McCluskey, J. (2006) A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition, Journal of Experimental Medicine, 203, 661-673. Link to full text
Konagurthu, A.S., Whisstock, J.C., Stuckey, P.J. and Lesk, A.M. (2006) MUSTANG: A Multiple Structural Alignment Algorithm, Proteins, 64, 559-574.
Kovacevic, S., Anderson, D., Morita, Y.S., Patterson, J., Haites, R., McMillan, B.N., Coppel, R.L., McConville, M.J. and Billman-Jacobe, H. (2006) Identification of a novel protein with a role in lipoarabinomannan biosynthesis in mycobacteria, Journal of Biological Chemistry, 281, 9011-9017.
Lan, R.Y., Cheng, C., Lian, Z.X., Tsuneyama, K., Yang, G.X., Moritoki, Y., Chuang, Y.H., Nakamura, T., Saito, S., Shimoda, S., Tanaks, A., Bowlus, C.L., Takano, Y., Ansari, A.A., Coppel, R.L. and Gershwin, M.E. (2006) Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis, Hepatology, 43, 729-737.
Law, R.H., Zhang, Q., McGowan, S., Buckle, A.M., Silverman, G.A., Pike, R.N., Bottomley, S.P., Bird, P.I. and Whisstock, J.C. (2006) An Overview of the Serpin Superfamily, Genome Biology, 7, 216.
Lew, R.A., Warner, F.J., Hanchapola, I., and Smith, A.I. (2006) Characterization of angiotensin converting enzyme-2 (ACE2) in human urine, International Journal of Peptide Research and Therapeutics, 12, 283-289.
Lim, M.L.R., Chen, B., Beart, P.M. and Nagley, P. (2006) Relative timing of redistribution of cytochrome c and Smac/DIABLO from mitochondria during apoptosis assessed by double immunocytochemistry on mammalian cells, Experimental Cell Research, 312, 1174-1184.
Lo, M., Bulach, D.M., Powell, D.R., Haake, D.A., Matsunaga, J., Paustian, M.L., Zuerner, R.L. and Adler B. (2006) Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole genome microarrays, Infection and Immunity, 74, 5848-5859. Link to full text
Marland, Z., Beddoe, T., Zaker-Tabrizi, L., Lucet, I.S., Brammananth, R., Whisstock, J.C., Wilce, M.C.J., Coppel, R.L., Crellin, P.K. and Rossjohn, J. (2006) Hijacking of a substrate-binding protein scaffold for us in mycobacterial cell wall biosynthesis, Journal of Molecular Biology, 359, 983-997.
McGowan, S., Buckle, A.M., Irving, J.A., Ong, P.C., Bashtannyk-Puhalovich, T.A., Kan, W.T., Henderson, K.N., Bulynko, Y.A., Popova, E.Y., Smith, A.I., Bottomley, S.P., Rossjohn, J., Grigoryev, S.A., Pike, R.N. and Whisstock, J.C. (2006) X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation, EMBO Journal, 25, 3144-3155. Link to full text
Mijaljica, D., Prescott, M. and Devenish, R.J. (2006) Endoplasmic reticulum and Golgi complex: contributions to, and turnover by, autophagy, Traffic, 7, 1590-1595.
Miles, J.J., Borg, N.A., Brennan, R.M., Tynan, F.E., Kjer-Nielsen, L., Silins, S.L., Bell, M.J., Burrows, J.M., McCluskey, J., Rossjohn, J. and Burrows, S.R. (2006) TCRα Genes Direct MHC-restriction in the Potent Human T cell Response to a Class-I-bound Viral Epitope, Journal of Immunology, 177, 6804-6814.
Myers, G.S.A., Rasko, D.A., Cheung, J.K., Ravel, J., Seshadri, R., DeBoy, R., Varga, J., Awad, M.M., Brinkac, L., Daugherty, S., Dodson, B., Madupu, R., Nelson, W., Rosovitz, M.J., Sullivan, S., Khouri, H., Dimitrov, G., Watkins, K., Mulligan, S., Benton, J., Hiscox, T.J., Jost, H., Billington, S., Songer, J.G., McClane, B.A., Titball, R., Rood, J.I., Melville, S. and Paulsen, I.T. (2006) Skewed genomic variability between strains of the toxigenic bacterial pathogen, Clostridium perfringens, Genome Research, 16, 1031-1040. Link to full text
O'Connor, J., Lyras, D., Farrow, K.A., Adams, V., Powell, D.R., Hinds, J., Cheung, J.K. and Rood, J.I. (2006) Construction and analysis of chromosomal C. difficile mutants, Journal of Molecular Microbiology, 61, 1335-1351.
Oertelt, S., Lian, Z.X., Cheng, C.M., Chuang, Y.H., Padgett, K.A., He, X.S., Ridgway, W.M., Ansari, A.A., Coppel, R.L., Li, M.O., Flavell, R.A., Kronenberg, M., Mackay, I.R. and Gershwin, M.E. (2006) Anti-Mitochondrial Antibodies and Primary Biliary Cirrhosis in TGF-beta Receptor 11 Dominant-Negative Mice, Journal of Immunology, 177, 1655-1660.
Olsen, S., Prescott, M., Wilmann, P., Battad, J., Rossjohn, J. and Smith, S.C. (2006) Determination of chromophore charge states in the low pH color transition of the fluorescent protein Rtms5 (HI46S) via time-dependent DFT, Chemical Physics Letters, 420, 507-511.
Parker, D., Kennan, R.M., Myers, G.S., Paulsen, I.T., Songer, J.G. and Rood, J.I. (2006) Regulation of the fimbrial biogenesis in Dichelobacter nodosus, Journal of Bacteriology, 188, 4801-4811. Link to full text
Paton, A.W., Beddoe, T., Thorpe, C.M., Whisstock, J.C., Wilce, M.C.J., Rossjohn, J., Talbot, U.M. and Paton, J.C. (2006) AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP, Nature, 443, 548-552.
Plebanski, M., Loopez, E., Proudfoot, O., Cooke, B.M., Itzstein, M. and Coppel, R.L. Economic and practical challenges to the formulation of vaccines against endemic infectious diseases such as malaria, Methods, 40, 77-85.
Rieger, R., Leung, P.S., Jeddeloh, M.R., Jurth, M.J., Nantz, M.H., Lam, K.S., Barsky, D., Ansari, A.A., Coppel, R.L., Mackay, I.R. and Gershwin, M.E. (2006) Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis, Journal of Autoimmunity, 27, 7 -16.
Sanders, P.R., Kats, L.M., Drew, D.R., O’Donnell, R.A., O’Neill, M., Maier, A.G., Coppel, R.L. and Crabb, B.S. (2006) A set of glycosylphosphatidyl inositol-anchored membrane proteins of Plasmodium falciparum is refractory to genetic deletion, Infection and Immunity, 74, 4330-4338. Link to full text
Shen, Y., Cranmer, S.L., Aprico, A., Whisstock, J.C., Jackson, S.P., Berndt, M.C. and Andrews, R.K. (2006) Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ib alpha regulate shear-dependent cell adhesion to von Willebrand factor, Journal of Biological Chemistry, 281, 26419-26423.
Smith, A.I., Lew, R.A., Thomas, W.G. and Tochon-Danguy, N. (2006) Protein kinase C regulates the cell surface activity of endothelin-converting enzyme-1, International Journal of Peptide Research and Therapeutics, 12, 291-295.
Sullivan, L.C., Hoare, H., Rossjohn, J. and Brooks, A.G. (2006) A structural perspective on MHC class Ib molecules in adaptive immunity, Trends in Immunology, 27, 413-420.
Tan, L.C., Kuruppua, S., Smith, A.I, Reeve, S. and Hodgson, W.C. (2006) Isolation and pharmacological characterisation of hostoxin-1, a postsynaptic neurotoxin from the venom of the Stephen's banded snake (Hoplecephalus stephensi), Neuropharmacology, 51, 782-788.
Tikellis, C., Cooper, M.E., Bialkowski, K., Johnston, C.I., Burns, W.C., Lew, R.A., Smith, A.I. and Thomas, M.C. Developmental (2006) Expression of ACE2 in the SHR Kidney: A role in hypertension? Kidney International, 70, 34-41.
Turcic, K., Pettikiriarachchi, A., Battad, J., Wilmann, P.G., Rossjohn, J., Dove, S.G., Devenish, R.J. and Prescott, M. (2006) Amino acid substitutions around the chromophore of the chromoprotein Rtms5 influence polypeptide cleavage, Biochemical and Biophysical Research Communications, 340, 1139-1143.
Turner, S.J., Doherty, P.C., McCluskey, J. and Rossjohn, J. (2006) Structural determinants of T cell bias, Nature Reviews Immunology, 6, 883-894.
van Ulsen, P., Adler, B., Fassler, P., Gilbert, M., van Schilfgaarde, M., van der Ley, P., van Alphen, L. and Tommassen, J. (2006) A novel phase-variable autotransporter serine protease, AusI, of Neisseria meningitidis, Microbes and Infection, 8, 2088-2097.
Wakabayashi, K., Lian, Z.X., Moritoki, Y., Lan, R.Y., Tsuneyama, K., Chuang, Y.H., Yang, G.X., Ridgway, W., Ueno, Y., Ansari, A.A., Coppel, R.L., Mackay, I.R. and Gershwin, M.E. (2006) IL-2 receptor alpha (-/-) mice and the development of primary biliary cirrhosis, Hepatology, 44, 1240-1249.
Wang, Y., Liu, V.W.S., Tsang, P.C.K., Chiu, P.M., Cheung, A.N.Y., Khoo, U.S., Nagley, P. and Ngan, H.Y.S. (2006) Microsatellite instability in mitochondrial genome of common female cancers, International Journal of Gynecological Cancer, 16, 259-266.
Whisstock, J.C. and Bottomley, S.P. (2006) Molecular Gymnastics: serpin structure folding and misfolding, Current Opinion in Structural Biology, 16, 761-768.
Williamson, N.A., Rossjohn, J. and Purcell, A.W. (2006) Tumors reveal their secrets to cytotoxic T cells, Proceedings of the National Academy of Sciences of the United States of America, 103, 14649-14650. Link to full text
Wilmann, P.G., Battad, J., Beddoe, T., Olsen, S., Smith, S.C., Dove, S., Devenish, R.J., Rossjohn, J. and Prescott, M. (2006) The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding, Photochemistry and Photobiology, 82, 359-366.
Wilmann, P.G., Battad, J., Petersen, J., Wilce, M.C.J., Dove, S., Devenish, R.J., Prescott, M. and Rossjohn, J. (2006) An atypical GFP chromophore environment revealed from the 2.1Å crystal structure of copGFP, a holotypic member of the Copepodan clade within the Green Fluorescent Protein superfamily, Journal of Molecular Biology, 359, 890-900.
Wilmann, P.G., Turcic, K., Battad, J.M., Wilce, M.C., Devenish, R.J., Prescott, M. and Rossjohn, J. (2006) The 1.7A Crystal Structure of Dronpa: A Photoswitchable Green Flourescent Protein, Journal of Molecular Biology, 364, 213-224.
Wilson, K.M., Smith, A.I. and Philips, D.J. (2006) Stimulatory effects of lipopolysaccharide on endothelial cell activin and follistatin, Molecular and Cellular Endocrinology, 253, 30-35.
Witchell, T.D., Coutts, S.A.J., Bulach, D.M. and Adler, B. (2006) Differential expression of the Bhmp39 major outer membrane proteins of Brachyspira hyodysenteriae, Infection and Immunity, 74, 3271-3276. Link to full text