2008 Refereed Papers
Archbold, J.K., Macdonald, W.A., Burrows, S.R., Rossjohn, J. & McCluskey, J. (2008) T-cell allorecognition: a case of mistaken identity or deja vu? Trends in Immunology, 29, 220-6.
Butler, N.S., Theodossis, A., Webb, A.I., Dunstone, M.A., Nastovska, R., Ramarathinam, S.H., Rossjohn, J., Purcell A.W. & Perlman, S. (2008) Structural and Biological Basis of CTL Escape in Coronavirus-Infected Mice. Journal of Immunology, 180, 3926-3937.
Crellin, P.K., Kovacevic, S., Martin, K.L., Brammananth, R., Morita, Y.S., Billman-Jacobe, H., McConville, M.J. & Coppel, R.L. (2008) Mutations in pimE restore lipoarabinomannan synthesis and growth in a Mycobacterium smegmatis lpqW mutant. Journal of Bacteriology, 190, 3690-3699.
Cullinane, M., Gong, L., Li, X, Lazar-Adler, N., Tra, T., Wolvetang, E., Prescott, M., Boyce, J.D., Devenish, R.J. & Adler, B. Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines. Autophagy, 4, 744-753.
Fulton (nee Marland), Z., McAlister, A., Wilce, M.C.J., Brammananth, R., Zaker-Tabrizi, L., Perugini, M.A., Bottomley, S.P., Coppel, R.L., Crellin, P.K., Beddoe, T. & Rossjohn, J. (2008) Crystal structure of a UDP-glucose specific glycosyltransferase from a mycobacterium species. Journal of Biological Chemistry, Jul 30 [Epub ahead of print].
Godfrey, D.I., Rossjohn, J. & McCluskey, J. (2008) The fidelity, occasional promiscuity, and versatility of T cell receptor recognition. Immunity, 28, 304-314.
Gras, S., Kjer-Nielsen, L., Burrows, S.R., McCluskey, J. & Rossjohn, J. T-cell receptor bias and immunity. Current Opinion in Immunology, 20, 119-125.
Han, X., Kennan, R.M., Davies, J.K., Reddacliff, L.A, Dhungyel, O.P, Whittington, R.J., Turnbull, L., Whitchurch, C.B & Rood, J.I. (2008) Twitching motility is essential for virulence in Dichelobacter nodosus. Journal of Bacteriology, 190, 3323-3335.
Hoke, D.E., Egan, S., Cullen, P.A. & Adler, B. (2008) LipL32 is an extracellular matrix-interacting protein of Leptospira and Pseudoalteromonas tunicata. Infecion and Immunity, 76, 2063-2069.
Howden, B.P., Smith, D.J., Mansell, A., Johnson, P.D.R., Ward, P.B., Stinear, T.P. & Davies, J.K. (2008) Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia. BMC Microbiology, 8, 39. Link to full text
Keyburn, A.L., Boyce, J.D., Vaz, P., Bannam, T.L, Ford, M.E, Parker, D., Di Rubbo, A., Rood, J.I & Moore, R.J. (2008) NetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens. PLoS Pathogens, 4, e26. Link to full text
Klionsky, D.J, Abeliovich, H., Agostinis, P., Agrawal, D.K., Aliev, G., Askew, D.S., Baba, M., Baehrecke, E.H., Bahr, B.A., Ballabio, A., Bamber, B.A., Bassham, D.C., Bergamini, E., Bi, X., Biard-Piechaczyk, M., Blum, J.S., Bredesen, D.E., Brodsky, J.L., Brumell, J.H., Brunk, U.T., Bursch, W., Camougrand, N., Cebollero, E., Cecconi, F., Chen, Y., Chin, L.S., Choi, A., Chu, C.T., Chung, J., Clarke, P.G., Clark, R.S., Clarke, S.G., Clavé, C., Cleveland, J.L., Codogno, P., Colombo, M.I., Coto-Montes, A., Cregg, J.M., Cuervo, A.M., Debnath, J., Demarchi, F., Dennis, P.B., Dennis, P.A., Deretic, V., Devenish, R.J., Di Sano, F., Dice, J.F., Difiglia, M., Dinesh-Kumar, S., Distelhorst, C.W., Djavaheri-Mergny, M., Dorsey, F.C., Dröge, W., Dron, M., Dunn, W.A. Jr, Duszenko, M., Eissa, N.T., Elazar, Z., Esclatine, A., Eskelinen, E.L., Fésüs, L., Finley, K.D., Fuentes, J.M., Fueyo, J., Fujisaki, K., Galliot, B., Gao, F.B., Gewirtz, D.A., Gibson, S.B., Gohla, A., Goldberg, A.L., Gonzalez, R., González-Estévez, C., Gorski, S., Gottlieb, R.A., Häussinger, D., He, Y.W., Heidenreich, K., Hill, J.A., Høyer-Hansen, M., Hu, X., Huang, W.P., Iwasaki, A., Jäättelä, M., Jackson, W.T., Jiang, X., Jin, S., Johansen, T., Jung, J.U., Kadowaki, M., Kang, C., Kelekar, A., Kessel, D.H., Kiel, J.A., Kim, H.P., Kimchi, A., Kinsella, T.J., Kiselyov, K., Kitamoto, K., Knecht, E., Komatsu, M., Kominami, E., Kondo, S., Kovács, A.L., Kroemer, G., Kuan, C.Y., Kumar, R., Kundu, M., Landry, J., Laporte, M., Le, W., Lei, H.Y., Lenardo, M.J., Levine, B., Lieberman, A., Lim, K.L., Lin, F.C., Liou, W., Liu, L.F., Lopez-Berestein, G., López-Otín, C., Lu, B., Macleod, K.F., Malorni, W., Martinet, W., Matsuoka, K., Mautner, J., Meijer, A.J., Meléndez, A., Michels, P., Miotto, G., Mistiaen, W.P., Mizushima, N., Mograbi, B., Monastyrska, I., Moore, M.N., Moreira, P.I., Moriyasu, Y., Motyl, T., Münz, C., Murphy, L.O., Naqvi, N.I., Neufeld, T.P., Nishino, I., Nixon, R.A., Noda, T., Nürnberg, B., Ogawa, M., Oleinick, N.L., Olsen, L.J., Ozpolat, B., Paglin, S., Palmer, G.E., Papassideri, I., Parkes, M., Perlmutter, D.H., Perry, G, Piacentini, M, Pinkas-Kramarski, R, Prescott, M, Proikas-Cezanne, T, Raben, N., Rami, A., Reggiori, F., Rohrer, B., Rubinsztein, D.C., Ryan, K.M., Sadoshima, J., Sakagami, H., Sakai, Y., Sandri, M., Sasakawa, C., Sass, M., Schneider, C., Seglen, P.O., Seleverstov, O., Settleman, J., Shacka, J.J., Shapiro, I.M., Sibirny, A., Silva-Zacarin, E.C., Simon, H.U., Simone, C., Simonsen, A., Smith, M.A., Spanel-Borowski, K., Srinivas, V., Steeves, M., Stenmark, H., Stromhaug, P.E., Subauste, C.S., Sugimoto, S., Sulzer, D., Suzuki, T., Swanson, M.S., Tabas, I., Takeshita, F., Talbot, N.J., Tallóczy, Z., Tanaka, K., Tanida, I., Taylor, G.S., Taylor, J.P., Terman, A., Tettamanti, G., Thompson, C.B., Thumm, M., Tolkovsky, A.M., Tooze, S.A., Truant, R., Tumanovska, L.V., Uchiyama, Y., Ueno, T., Uzcátegui, N.L., van der Klei, I., Vaquero, E.C., Vellai, T., Vogel, M.W., Wang, H.G., Webster, P., Wiley, J.W., Xi, Z., Xiao, G., Yahalom, J., Yang, J.M., Yap, G., Yin, X.M., Yoshimori, T., Yu, L., Yue, Z., Yuzaki, M., Zabirnyk, O., Zheng, X., Zhu, X. & Deter, R.L. (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy, 4, 151-175.
Lea-Smith, D.J., Martin, K.L., Pyke, J.S., Tull, D., McConville, M.J., Coppel, R.L. & Crellin, P.K. (2008) Analysis of a new mannosyltransferase required for the synthesis of phosphatidylinositol mannosides and lipoarbinomannan reveals two lipomannan pools in corynebacterineae. Journal of Biological Chemistry, 283, 6773-6782.
Murray, G.L., Ellis, K.M., Lo, M. & Adler, B. (2008) Leptospira interrogans requires a functional heme oxygenase to scavenge iron from hemoglobin. Microbes and Infection/Institut Pasteur, 10, 791-797.
Picardeau, M, Bulach, D.M., Bouchier, C., Zuerner, R.L., Zidane, N., Wilson, P.J., Creno, S., Kuczek, E.S., Bommezzadri, S., Davis, J.C., McGrath, A., Johnson, M.J., Boursaux-Eude, C., Seemann, T., Rouy, Z., Coppel, R.L., Rood, J.I., Lajus, A., Davies, J.K., Médigue, C. & Adler, B. (2008) Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. PloS ONE, 3, e1607.
Rosado, C., Kondos, S., Bull, T.E., Kuiper, M.J., Law, R.H., Buckle, A.M., Voskoboinik, I., Bird, P.I., Trapani, J.A., Whisstock, J.C. & Dunstone, M.A. The MACPF/CDC family of pore forming toxins. Cellular Microbiology, Jul 9 [Epub ahead of print].
Rosado, C., Mijaljica, D., Hatzinisiriou, I., Prescott, M., and Devenish, R.J. (2008) Rosella - a fluorescent pH-biosensor for reporting vacuolar turnover of cytosol and organelles in yeast. Autophagy, 4, 205-213.
Sansom, F.M., Riedmaier, P., Newton, H.J, Dunstone, M.A, Muller, C.E, Stephan, H., Byres, E., Beddoe, T., Rossjohn, J., Cowan, P.J, d'Apice, A.J., Robson, S.C & Hartland, E.L. (2008) Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila; substrate specificity and requirement for virulence. Journal of Biological Chemistry, 283, 12909-12918.
Sayeed, S., Uzal, F.A, Fisher, D.J., Saputo, J., Vidal, J.E., Fernandez-Miyakawa, M.E, Chen, Y., Gupta, P., Rood, J.I. & McClane, B.A. (2008) Beta toxin is essential for the virulence of Clostridium perfringens Type C isolate CN3685 in a rabbit ileal loop model. Molecular Microbiology, 67, 15-30.
Schmidberger, J.W., Wilce, J.A., Weightman, A.J., Whisstock, J.C. & Wilce, M.C. The crystal structure of DehI reveals a new alpha-haloacid dehalogenase fold and active-site mechanism. Journal of Molecular Biology, 378, 284-94.
Smith, D.P., Tew, D.J., Hill, A.F., Bottomley, S.P, Masters, C.L, Barnham, K.J. & Cappai, R. (2008) Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein. Biochemistry, 47, 1425-1434.
Smith, D.J, Ng, H., Kluck, R.M & Nagley, P. (2008) The mitochondrial gateway to cell death. IUBMB Life, 60, 383-389.
Sofian, T., Kan, W-T., Horvath, A.J., Hitchen, C.R., Langendorf, C.G., Buckle, A.M., Whisstock, J.C. & Coughlin, P.B. (2008) X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin. Blood, 111, 2049-2052.
Stinear, T.P., Seemann, T., Harrison, P.F, Jenkin, G.A, Davies, J.K., Johnson, P.D.R., Abdellah, Z., Arrowsmith, C., Chillingworth, T., Churcher, C., Clarke, K., Cronin, A., Davis, P., Goodhead, I., Holroyd, N., Jagels, K., Lord, A., Moule, S., Mungall, K., Norbertczak, H., Quail, M.A, Rabbinowitsch, E., Walker, D., White, B., Whitehead, S., Small, P.L.C, Brosch, R., Ramakrishnan, L., Fischbach, M.A, Parkhill J. & Cole, S.T. (2008) Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. Genome Research, 18, 729-741.
Teng, W.L., Bannam, T.L., Parsons, J.A, & Rood, J.I. (2008) Functional characterisation and localisation of the TcpH conjugation protein from Clostridium perfringens. Journal of Bacteriology, 190, 5075-5086.
Wun, K.S., Borg, N.A., Kjer-Nielsen, L., Beddoe, T., Koh, R., Richardson, S.K., Thakur, M., Howell, A.R, Scott-Browne, J.P, Gapin, L., Godfrey, D.I, McCluskey, J. & Rossjohn, J. (2008) A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. Journal of Experimental Medicine, 205, 939-949.
Wynn, K.K., Marland, Z., Cooper, L., Silins, S.L, Gras, S., Archbold, J.K., Tynan, F.E, Miles, J.J, McCluskey, J., Burrows, S.R, Rossjohn, J. & Khanna, R. (2008) Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection. Blood, 111, 4283-4292.
Zhang, Q., Law, R.H., Bottomley, S.P., Whisstock, J.C. & Buckle, A.M. (2008) A structural basis for loop C-sheet polymerization in serpins. Journal of Molecular Biology, 376, 1348-1359.